Is having the Sun, Mercury, Saturn, and Moon in the 8th house for a Virgo ascendant positive or negative in life?

For a Virgo Ascendant, the 8th House is the Zodiac of Aries (ruled by Mars)

In this Zodiac,

• Saturn is debilitated (loses most of its strength)
• Sun is exalted (gains more strength)

Now coming to what might be said with regards to the combination

1. The individual is a Aries Moon Sign and despite high energy to do things, they will feel ups & downs with regards to their motivation levels
2. If Sun is placed well, the individual will do well in areas linked to Engineering Roles (Oil & Gas, Mining, Machinery development, Manufacturing, etc.)
3. The dignity of Mercury is essential as the individual will be aided positively in their career growth
4. Keeping tempered expectations and maintaining discipline will aid in growth in all aspects of life

Hope this helps

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You can read more on different combinations linked to astrology through the following links:

• Quora Posts – Lateral Thinking
• Understanding Ketu Through Vedic Astrology: Knowing About the Shadow Planet That Rules ‘Moksha’ (Kindle E-Book)

All the Best

God Bless!