What makes some houses in a birth chart more powerful than others?

If we look from only the house perspective, the most important houses

1. House 6
2. House 8
3. House 12

All three are Dusthana houses but they carry a lot of heft interms of outcome for an individual

House 6

• Linked to Service, Debt, Obstacles, Diseases
• Linked to small animals like Dogs, Cats, Hamsters

Why this is important:

• Blessings from the 5th house is put into effect through the 2nd House from it – which is the 6th House. So application of talent & skills is the 6th House
• Ability to face or overcome or type of troubles in life that you will face will be seen in the 6th House which aids the individual on how to manage & tackle it

House 8

• Linked to life post marriage, in-laws, joint assets, one-time gains in life
• Linked to surgeries, accidents, death, transformative experiences, occult

Why this is important:

• Karma linked to the 7th house(partnership – legal & marital) is put into affect through the 2nd House from it – which is the 8th House. So application of partnership is seen in the 8th House
• Understanding, Growth, Transformation will be seen in the 8th House which aids the individual to grow, curtail or detach from the partnership

House 12

• Linked to spiritual growth, understanding the meaning of life
• Linked to loss, hospitals, asylums, isolation

Why this is important:

• Aspirations linked to the 11th house(dreams and wishes) is put into affect through the 2nd House from it – which is the 12th House. So the outcome of aspirations is seen in the 12th House
• Understanding that life is a journey and doing our karma is the only thing in our hand is the best way to achieve outcomes linked to the 11th by understanding the 12th house

Hope this gives an understanding as to why Dusthana Houses (6, 8, 12) are crucial for an individual and be considered powerful as they bring growth in an individual through an obstacle course like gamification approach.

Hope this helps

You can read more on different combinations linked to astrology through the following links:

Quora Posts – Lateral Thinking

All the Best

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God Bless!